厚壁菌門中的腸道羅斯拜瑞氏菌(Roseburia?intestinalis),是常見的產(chǎn)丁酸菌,是人體腸道內(nèi)降解膳食纖維木聚糖的關(guān)鍵細(xì)菌之一。Nature Microbiology上周發(fā)表的一項研究,詳細(xì)解析了這種菌如何將木聚糖分解為木寡糖并內(nèi)化、分解的分子機制,并發(fā)現(xiàn)其與另一種木聚糖降解菌有不同的木寡糖利用偏好,從而使二者在利用膳食木聚糖時可以實現(xiàn)共同生長的雙贏局面。
基本信息
平臺編號:bio-104720
規(guī)格:0
拉丁屬名:Roseburia intestinalis
詳情介紹
Roseburia intestinalis Duncan et al. 2002
Taxonomy in NCBI database: Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae.
31262 <-- T. Lawley; Wellcome Trust Sanger Inst., UK; Sanger_113.
Accessioned in 2016.
Medium: 1130; Temperature: 37°C; Anaerobic; Rehydration fluid: 663.
open link in new window
Source: Human feces [11064].
Publication(s) using this strain [C16543].
Delivery category: Domestic, A or C; Overseas, A or C.
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
腸道羅斯拜瑞氏菌如何利用和降解膳食木聚糖
①腸道羅斯拜瑞氏菌是降解膳食纖維木聚糖的關(guān)鍵腸道菌之一,可在多種木聚糖上生長,但偏好阿拉伯木聚糖;
②附于細(xì)菌表面的木聚糖酶RiXyn10A含有4個木聚糖結(jié)合模塊,可捕獲木聚糖分子,將之水解為木寡糖;
③經(jīng)ABC轉(zhuǎn)運體被細(xì)菌攝取,之后多種水解酶和乙酰酯酶參與木寡糖的降解;
④腸道羅斯拜瑞氏菌的ABC轉(zhuǎn)運體主要攝取含4-5個木糖的木寡糖,與另一種降解木聚糖的擬桿菌對木寡糖的偏好不同,兩種菌可在混合木聚糖培養(yǎng)基中共生長。
中國微生物菌種查詢網(wǎng)作為中國微生物菌種中心引航者,單位代為引進(jìn)美國ATCC微生物菌種保藏中心,德國DSMZ菌種保藏中心,荷蘭CBS菌種保藏中心,日本JCM微生物菌種保藏中心,包括其中的ATCC微生物細(xì)菌與噬菌體(18382);細(xì)胞系和雜交瘤(4997);真菌和酵母(58183);原代細(xì)胞(146);原生動物和藻類(2428);干細(xì)胞(102);載體,克隆與分子(18006);病毒(3594);核酸 - DNA / RNA(1350),引進(jìn)進(jìn)口微生物菌種貨期短,質(zhì)量保證,UPS國際快遞運輸。