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平臺編號：bio-69703
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細(xì)胞信息： SYF
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規(guī)格：1×10?cells/T25培養(yǎng)瓶
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用途：/
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服務(wù)費(fèi)用：
加載中…… - 訂購
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注意事項(xiàng)：僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類或動物的臨床診斷或治療，非藥用，非食用（產(chǎn)品信息以出庫為準(zhǔn)）
SYF（小鼠胚胎成纖維細(xì)胞（SV40））
SYF（小鼠胚胎成纖維細(xì)胞（SV40））
產(chǎn)品類別：小鼠細(xì)胞系
生長特性：貼壁生長
細(xì)胞形態(tài)：Fibroblast
凍存條件：90%FBS+10%DMSO
Synonyms: SYF(小鼠胚胎成纖維細(xì)胞（SV40）)
Background: SYF (deficient for Src, Yes, and Fyn) cells were generated in 1997 from mouse embryos harboring functional null mutations in both alleles of the Src family protein tyrosine kinases, Src, Yes, and Fyn.
The cells were immortalized before passage 2 by infection with a retroviral vector transducing the SV40 large T antigen. SYF cells also carry a gene for neomycin resistance.
Species: Mus musculus, mouse
Tissue: embryo
Gender: 9 days gestation
Morphology: fibroblast
Growth Mode: adherent
Culture Medium: DMEM+10%FBS
We strongly suggest to purchase the complete medium
Cryopreservation medium: 90%FBS+10%DMSO
Oncogene: src -; yes -; fyn -
Comments: Src family kinases have been implicated as key regulators of ligand-induced cellular responses including proliferation, survival, adhesion and migration.
This is the first cell line isolated that lacks all three ubiquitously expressed Src family members.
SYF cells display reduced mobility in wound healing and haptotaxis assays but not in platelet derived growth factor (PDGF) induced chemotaxis.
產(chǎn)品類別：小鼠細(xì)胞系
生長特性：貼壁生長
細(xì)胞形態(tài)：Fibroblast
凍存條件：90%FBS+10%DMSO
Synonyms: SYF(小鼠胚胎成纖維細(xì)胞（SV40）)
Background: SYF (deficient for Src, Yes, and Fyn) cells were generated in 1997 from mouse embryos harboring functional null mutations in both alleles of the Src family protein tyrosine kinases, Src, Yes, and Fyn.
The cells were immortalized before passage 2 by infection with a retroviral vector transducing the SV40 large T antigen. SYF cells also carry a gene for neomycin resistance.
Species: Mus musculus, mouse
Tissue: embryo
Gender: 9 days gestation
Morphology: fibroblast
Growth Mode: adherent
Culture Medium: DMEM+10%FBS
We strongly suggest to purchase the complete medium
Cryopreservation medium: 90%FBS+10%DMSO
Oncogene: src -; yes -; fyn -
Comments: Src family kinases have been implicated as key regulators of ligand-induced cellular responses including proliferation, survival, adhesion and migration.
This is the first cell line isolated that lacks all three ubiquitously expressed Src family members.
SYF cells display reduced mobility in wound healing and haptotaxis assays but not in platelet derived growth factor (PDGF) induced chemotaxis.
