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平臺編號：bio-129560
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細(xì)胞信息： IGR-1
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規(guī)格：1×10?cells/T25培養(yǎng)瓶
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用途：細(xì)胞系
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服務(wù)費(fèi)用：
加載中…… - 訂購
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注意事項(xiàng)：僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類或動(dòng)物的臨床診斷或治療，非藥用，非食用（產(chǎn)品信息以出庫為準(zhǔn)）
人黑色素瘤細(xì)胞IGR-1
細(xì)胞名稱：人黑色素瘤細(xì)胞IGR-1
產(chǎn)品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細(xì)胞數(shù)量：1x10^6；1x10^6
保存溫度：37℃；-198℃
運(yùn)輸方式：常溫保溫運(yùn)輸；干冰運(yùn)輸
安全等級：1
用途限制：僅供科研4類
培養(yǎng)體系：DMEM高糖培養(yǎng)基（不含丙酮酸鈉）+10%FBS+1%三抗
培養(yǎng)溫度：37℃
二氧化碳濃度：5%
簡介：人黑色素瘤細(xì)胞IGR-1取自42歲男性供體。為黑色素瘤腹股溝淋巴結(jié)轉(zhuǎn)移株。
注釋：Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Part of:COSMIC cell lines project.
Doubling time:~75-100 hours(DSMZ).
Microsatellite instability:Stable(MSS)(Sanger).
Omics:Deep exome analysis.
Omics:Deep quantitative proteome analysis.
Omics:Deep RNAseq analysis.
Omics:DNA methylation analysis.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
突變信息
Mutation;HGNC;1097;BRAF;Simple;p.Val600Lys(c.1798_1799delGTinsAA);ClinVar=VCV000375941;Zygosity=Heterozygous(PubMed=25056119;CCLE;Cosmic-CLP).
Mutation;HGNC;9801;RAC1;Simple;p.Pro29Ser(c.85C>T);ClinVar=VCV000376362;Zygosity=Heterozygous(PubMed=25056119;CCLE;Cosmic-CLP).
STR信息
Amelogenin X,Y
CSF1PO 10
D3S1358 14,17
D5S818 10,11(CLS;Cosmic-CLP;DSMZ;PubMed=25877200)
10,14(PubMed=25056119)
D7S820 10,11
D8S1179 10(CLS)
10,14(PubMed=25056119;PubMed=25877200)
D13S317 13
D16S539 11(PubMed=25056119)
11,13(CLS;Cosmic-CLP;DSMZ;PubMed=25877200)
D18S51 14,16(PubMed=25877200)
16(CLS)
D21S11 32.2
FGA 23,24
Penta D 10
Penta E 7,11
TH01 7,9.3(CLS)
9.3(Cosmic-CLP;DSMZ;PubMed=25056119;PubMed=25877200)
TPOX 8
vWA 17,18(CLS;Cosmic-CLP;DSMZ;PubMed=25877200)
18(PubMed=25056119)
參考文獻(xiàn)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.-H.,Monteiro A.N.A.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
PubMed=31978347;DOI=10.1016/j.cell.2019.12.023
Nusinow D.P.,Szpyt J.,Ghandi M.,Rose C.M.,McDonald E.R.III,Kalocsay M.,Jane-Valbuena J.,Gelfand E.,Schweppe D.K.,Jedrychowski M.,Golji J.,Porter D.A.,Rejtar T.,Wang Y.K.,Kryukov G.V.,Stegmeier F.,Erickson B.K.,Garraway L.A.,Sellers W.R.,Gygi S.P.
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)
細(xì)胞操作說明書下載：細(xì)胞操作說明書
產(chǎn)品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細(xì)胞數(shù)量：1x10^6；1x10^6
保存溫度：37℃；-198℃
運(yùn)輸方式：常溫保溫運(yùn)輸；干冰運(yùn)輸
安全等級：1
用途限制：僅供科研4類
培養(yǎng)體系：DMEM高糖培養(yǎng)基（不含丙酮酸鈉）+10%FBS+1%三抗
培養(yǎng)溫度：37℃
二氧化碳濃度：5%
簡介：人黑色素瘤細(xì)胞IGR-1取自42歲男性供體。為黑色素瘤腹股溝淋巴結(jié)轉(zhuǎn)移株。
注釋：Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Part of:COSMIC cell lines project.
Doubling time:~75-100 hours(DSMZ).
Microsatellite instability:Stable(MSS)(Sanger).
Omics:Deep exome analysis.
Omics:Deep quantitative proteome analysis.
Omics:Deep RNAseq analysis.
Omics:DNA methylation analysis.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
突變信息
Mutation;HGNC;1097;BRAF;Simple;p.Val600Lys(c.1798_1799delGTinsAA);ClinVar=VCV000375941;Zygosity=Heterozygous(PubMed=25056119;CCLE;Cosmic-CLP).
Mutation;HGNC;9801;RAC1;Simple;p.Pro29Ser(c.85C>T);ClinVar=VCV000376362;Zygosity=Heterozygous(PubMed=25056119;CCLE;Cosmic-CLP).
STR信息
Amelogenin X,Y
CSF1PO 10
D3S1358 14,17
D5S818 10,11(CLS;Cosmic-CLP;DSMZ;PubMed=25877200)
10,14(PubMed=25056119)
D7S820 10,11
D8S1179 10(CLS)
10,14(PubMed=25056119;PubMed=25877200)
D13S317 13
D16S539 11(PubMed=25056119)
11,13(CLS;Cosmic-CLP;DSMZ;PubMed=25877200)
D18S51 14,16(PubMed=25877200)
16(CLS)
D21S11 32.2
FGA 23,24
Penta D 10
Penta E 7,11
TH01 7,9.3(CLS)
9.3(Cosmic-CLP;DSMZ;PubMed=25056119;PubMed=25877200)
TPOX 8
vWA 17,18(CLS;Cosmic-CLP;DSMZ;PubMed=25877200)
18(PubMed=25056119)
參考文獻(xiàn)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.-H.,Monteiro A.N.A.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
PubMed=31978347;DOI=10.1016/j.cell.2019.12.023
Nusinow D.P.,Szpyt J.,Ghandi M.,Rose C.M.,McDonald E.R.III,Kalocsay M.,Jane-Valbuena J.,Gelfand E.,Schweppe D.K.,Jedrychowski M.,Golji J.,Porter D.A.,Rejtar T.,Wang Y.K.,Kryukov G.V.,Stegmeier F.,Erickson B.K.,Garraway L.A.,Sellers W.R.,Gygi S.P.
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)
細(xì)胞操作說明書下載：細(xì)胞操作說明書
