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Treponema denticola (ex Flügge) Chan et al. 拉丁名

(ATCC? 35405?) 統(tǒng)一編號

Deposited As Treponema denticola (Brumpt) Chen 

Strain Designations 菌種別名 a [CIP 103919, DSM 14222] 

Application 用途 Produces major surface protein Produces methyl-accepting chemotaxis protein Produces prolyl aminopeptidase proline iminopeptidase 

Isolation 分離源 Human periodontal pocket, Montreal, Canada 

Biosafety Level 生物安全等級 1 

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. 

Antigenic Properties serovar a 

Product Format 提供形式 freeze-dried 

Storage Conditions 保存方法 

Frozen 冷凍物 : -80°C or colder 

Freeze-Dried 凍干物 : 2°C to 8°C 

Live Culture 活菌 : See Propagation Section

Preceptrol? no 

Genome Sequenced Strain Treponema denticola ATCC 35405, complete genome. 

Type Strain 模式菌株 yes 

Antigenic Properties serovar a 

Comments 注釋 Benzoylarginine peptidase and iminopeptidase profiles 

Genome sequenced strain

Medium 培養(yǎng)基 ATCC? Medium 1494: Modified NOS medium 

ATCC? Medium 260: Trypticase soy agar/broth with defibrinated sheep blood 

Growth Conditions 生長條件

Temperature 培養(yǎng)溫度 : 37°C 

Atmosphere 需氧情況 : Anaerobic gas mixture, 80% N2-10% CO2-10% H2

Name of Depositor 寄存人 E Chan 

Isolation 分離源 Human periodontal pocket, Montreal, Canada 

References 參考文獻 Makinen KK, et al. Dominance of iminopeptidase activity in the human oral bacterium Treponema denticola ATCC 35405. Curr. Microbiol. 14: 341-346, 1987. 

Makinen KK, et al. Benzoylarginine peptidase and iminopeptidase profiles of Treponema denticola strains isolated from the human periodontal pocket. Curr. Microbiol. 14: 85-89, 1986. 

Makinen KK, et al. Proline iminopeptidase from the outer cell envelope of the human oral spirochete Treponema denticola ATCC 35405. Infect. Immun. 64: 702-708, 1996. PubMed: 8641769 

Chan EC, et al. Treponema denticola (ex Brumpt 1925) sp. nov., nom. rev., and identification of new spirochete isolates from periodontal pockets. Int. J. Syst. Bacteriol. 43: 196-203, 1993. PubMed: 8494734 

Cheng SL, et al. Comparative study of six random oral spirochete isolates. Serological heterogeneity of Treponema denticola. J. Periodontal Res. 20: 602-612, 1985. PubMed: 2935615 

Kataoka M, et al. Characterization of amethyl-accepting chemotaxis protein gene, dmcA, for the oral spirochete Treponema denticola. Infect. Immun. 65: 4011-4016, 1997. PubMed: 9317000 

Fenno JC, et al. Conservation of msp, the gene encoding the major outer membrane protein of oral Treponema spp. J. Bacteriol. 179: 1082-1089, 1997. PubMed: 9023187 

Ruby JD, et al. Relationship of Treponema denticola periplasmic flagella to irregular cell morphology. J. Bacteriol. 179: 1628-1635, 1997. PubMed: 9045823 

Walker SG, et al. Identification, isolation, and characterization of the 42-kilodalton major outer membrane protein (MompA) from Treponema pectinovorum ATCC 33768. J. Bacteriol. 179: 6441-6447, 1997. PubMed: 9335294 

Li H, et al. Gene inactivation in the oral spirochete Treponema denticola: construction of an flgE mutant. J. Bacteriol. 178: 3664-3667, 1996. PubMed: 8655571 

Roberts MC, et al. Characterization of tetracycline and erythromycin resistance determinants in Treponema denticola. Antimicrob. Agents Chemother. 40: 1690-1694, 1996. PubMed: 8807063 

Wyss C, et al. Treponema amylovorum sp. nov., a Saccharolytic spirochete of medium size isolated from an advanced human periodontal lesion. Int. J. Syst. Bacteriol. 47: 842-845, 1997. 

Seshadri R, et al. Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes. Proc. Natl. Acad. Sci. USA. 101(15): 5646-5651, 2004. PubMed: 15064399 

Cross References Nucleotide (GenBank) : U33210 dmcA 

Nucleotide (GenBank) : L36851 Treponema denticola fliG gene, complete cds. 

Nucleotide (GenBank) : L25421 Treponema denticola phosphatase gene, 5' end. 

Nucleotide (GenBank) : AF082511 Treponema denticola mgl operon, partial sequence. 

Nucleotide (GenBank) : U29399 Treponema denticola major outer sheath protein (msp) gene, complete cds. 

Nucleotide (GenBank) : L25603 Treponema denticola (ATCC 35405) chymotrypsin-like protease gene, complete cds. 

Nucleotide (GenBank) : U84257 Treponema denticola methyl-accepting chemotaxis protein B (dmcB) gene, partial cds. Nucleotide (GenBank) : AF012922 Treponema denticola methyl-accepting chemotaxis protein (mcpA) gene, complete cds. Nucleotide (GenBank) : AF042861 Treponema denticola OppA (oppA), putative OppB (oppB), putative OppC (oppC), putative OppD (oppD), and putative OppF (oppF) genes, complete cds. 

Nucleotide (GenBank) : AF232219 Treponema denticola putative alcohol dehydrogenase, FliQ (fliQ), FliR (fliR), and FlhB (flhB) genes, complete cds; and FlhA (flhA) gene, partial cds. 

Nucleotide (GenBank) : U78776 Treponema denticola gufa gene, partial cds, putative flagellar operon flgB, flgC, fliE, fliF, fliG, fliH, fliI and fliJ genes, complete cds, and fdgA gene, partial cds. 

Nucleotide (GenBank) : AF122909 Treponema denticola Tap1 (tap1), flagellar hook assembly scaffolding protein FlgD (flgD), flagellar hook protein FlgE (flgE), flagellar motor protein MotA (motA), flagellar motor protein MotB (motB), FliL (fliL), flagellar switch protein FliM 

Nucleotide (GenBank) : AF139203 Treponema denticola strain ATCC 35405 16S ribosomal RNA gene, partial sequence 

Nucleotide (GenBank) : AE017226 Treponema denticola ATCC 35405, complete genome.