ATCC? Number:VR-1464?
Classification: Picornaviridae, Enterovirus, Poliovirus
Agent: Human poliovirus 1 deposited as Poliovirus 1
Strain: Akron Ca23
Original Source: Stool from human with paralytic poliomyelitis
Depositors: GR Dubes
Biosafety Level:3
Shipped: frozen
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Host Organism : primary rhesus monkey cells; LLC-MK2 cells (ATCCCCL-7.1) primary rhesus monkey kidney cells; primary cynomolgus monkey kidney cells
Effect : Yes, in vitro effects: Cytopathic effects at 23 - 30C
Store at : -70C
Comments : Propagate at 23C. Can mutate to lose de-adaption to 37C. Propage at 23 C. Can mutate to lose de-adaption to 37 C.
References : 33192: Dubes GR, Wenner HA. Virulence of polioviruses in relation to variant characteristics distinguishable on cells in vitro. Virology 4: 275-296, 1957. PubMed: 13496545 33196: Wenner HA, et al. Antigenic variations among type 1 polioviruses; a study of 16 wild-type strains and 5 variants. Am. J. Hyg. 70: 66-90, 1959. PubMed: 13670168