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  • 平臺編號:bio-50013
  • 國際編號:ATCC VR-1457
  • 拉丁屬名: Human poliovirus 3
  • 規(guī)格:frozen
  • 用途:ATCC原裝進口
  • 服務(wù)費用:
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  • 訂購
  • 注意事項:僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類或動物的臨床診斷或治療,非藥用,非食用(產(chǎn)品信息以出庫為準(zhǔn))

ATCC? Number:VR-1457?
Classification: Picornaviridae, Enterovirus, Poliovirus
Agent: Human poliovirus 3 deposited as Poliovirus Type 3
Strain: Mabie Tr (tryptophan-requiring mutant)
Original Source: CNS tissue of human with bulobar poliovyelitis
Depositors: GR Dubes
Biosafety Level:3
Permits/Forms: In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
Host Organism : primary rhesus monkey kidney cells primary rhesus monkey kidney cells; primary cynomolgus monkey kidney cells
Incubation : Duration: 1-4 days at 37C
Effect : Yes, in vitro effects: Cytopathic effects with high L-tryptophan; slight or cryptic (stained cells in plaques) with low L-tryptophan
Store at : -70C
Comments : Requires high concentration of L-tryptophan for clear plaques at 37C, pH 7.0 - 7.5 on primary rhesus or cynomolgus monkey cells in tissue culture. Mutates to virus similar to wild type Mabie strain.
References : 33191: Dubes GR, et al. Antigenic variations among type 3 polioviruses. Am. J. Hyg. 70: 91-105, 1959. PubMed: 13670169 33192: Dubes GR, Wenner HA. Virulence of polioviruses in relation to variant characteristics distinguishable on cells in vitro. Virology 4: 275-296, 1957. PubMed: 13496545

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