ATCC® Number:VR-1587™
Classification: Paramyxoviridae, Paramyxovirinae, Morbillivirus
Agent: Canine distemper virus
Strain: Snyder Hill (cell culture adapted)
Depositors: LE Carmichael, ATCC
Biosafety Level:2
Shipped: frozen
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Tested Positive for Mycoplasma : No
Host Organism : Canis familiarisMustela putoris furoVulpes sp.
Incubation : Atmosphere: 5% CO2 in air recommended Temperature: 37.0°C Duration: 5-7 days
Effect : Yes, Cytopathic effect: vacuolization, rounding and sloughing of host cells
Store at : -70 or colder
Comments : VR-1587 was derived at the ATCCfrom VR-526 by adaptation to growth in Vero cells (ATCCCCL-81). VR-526, deposited by L. E. Carmichael, was originally isolated from the brain of a dog with clinical distemper in September, 1950.This virus produces neurological signs with regularity only when inoculated intracerebrally. It does not produce hemagglutinin or hemolysin. It is used primarily as a challenge strain to test dogs for immunity to the disease. Cross-immunity tests in dogs have shown this strain to be similar to other classical strains of CDV.
