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ATCC® Number:VR-356™
Agent: H-1 virus
Strain: Toolan
Original Source: Human embryo lung (4 months operative abortion) from mother with metastatic breast cancer, who had an HAI and neutralizing titer of 1:640 to H-1 virus
Depositors: HW Toolan
Biosafety Level:2
Shipped: frozen
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Host Organism : neonatal hamster; Chang Liver cells (ATCCCCL-13) hamster; human; rhesus monkey; rat
Incubation : Temperature: 37.0°C Duration: 5 days
Effect : Yes, in vitro effects: Cytopathic effects (cell death) in tissue culture Yes, in vivo effects: death or deformity of newborn hamster depending on virus concentration
Comments : Plaque purified on Salk MkHe. Hemagglutinates a variety of RBC, particularly guinea pig, hamster and human, and also has a CF antigen. Produces deformity or death in newborn hamsters and neutralizing antibodies in humans, monkeys, hamsters and rats. Plaque purified on Salk MkHe. Hemagglutinates a variety of RBC, particularly guinea pig, hamster and human, and also has a CF antigen. Produces deformity or death in newborn hamsters and neutralizing antibodies in humans, monkeys, hamsters and rats.
References : 33520: . . Proc. Am. Assoc. Cancer Res. 5: 64, 1964. 33521: . . Nature 208: 812, 1965.