ATCC® Number:VR-621™
Classification: Bunyaviridae
Agent: Lone star virus
Strain: TMA 1381
Original Source: A single nymphal Amblyomma americanum (Linn.) removed from a woodchuck, Kentucky, 1967
Depositors: Yale Arbovirus Research Unit
Biosafety Level:2
Shipped: freeze-dried
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Host Organism : suckling mouse, i.c. or i.p. inoculation; primary duck embryo cells; Vero cells (ATCCCCL-81); BHK-21(C-13) cells (ATCCCCL-10)
Incubation : Duration: 5 days
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture Yes, in vivo effects: Death in suckling mouse
Comments : Deoxycholate sensitive. No HA produced. Plaques in Vero and BHK-21 cells.
References : 24634: Kokernot RH, et al. Arbovirus studies in the Ohio-Mississippi Basin, 1964-1967. VII. Lone Star virus, a hitherto unknown agent isolated from the tick Amblyomma americanum (Linn). Am. J. Trop. Med. Hyg. 18: 789-795, 1969. PubMed: 5810802
